On-Demand Webinar – Optimising Nitric Oxide Donors Using Parallel Pressure Chemistry with ChemSCAN (UNC Schoenfisch Lab)

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Webinar – Optimising N-Diazeniumdiolate Nitric Oxide Donors Using Parallel Pressure Chemistry with ChemSCAN

Dr Maggie Purvis of the Schoenfisch Laboratory, University of North Carolina at Chapel Hill, presents her work on maximising nitric oxide donor formation while preserving the integrity of sensitive biomaterial scaffolds — using the H.E.L ChemSCAN parallel pressure reactor to screen reaction conditions in parallel. Includes a virtual tour of the Schoenfisch lab and a live Q&A.

Hosted by Dr Sina Ehsani, Americas Sales Manager, H.E.L Group. Recorded 23 June 2026 · 58 minutes.

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• 00:00 — Welcome and introduction
• 01:39 — Biological activity of nitric oxide
• 03:37 — Overview — combining NO with macromolecular scaffolds
• 05:10 — Wound healing
• 10:45 — Charging optimisation — maximising NO loading
• 13:59 — NO release from HA
• 15:24 — Tissue-based wound healing analysis
• 17:49 — NO-releasing HA as an immunomodulatory therapeutic
• 22:24 — In vitro immunomodulation
• 26:13 — Virtual tour of the Schoenfisch lab
• 30:39 — Anti-cancer NO-releasing materials
• 33:06 — Anti-cancer NO-releasing scaffolds
• 36:54 — In vivo anti-melanoma efficacy
• 38:25 — HA-coated nanoparticle synthesis
• 41:15 — Cellular uptake of HA-coated nanoparticles
• 42:50 — Conclusions
• 44:23 — Live Q&A

ChemSCAN is a parallel pressure reactor with eight independently controlled vessels, so reaction conditions can be varied per vessel and screened in one run. See the ChemSCAN →  ·  Ask a specialist →