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Webinar – Microbes in Motion: Continuous-Culture Bioreactors for Gut Microbiome Research

How do you study a gut microbial ecosystem that changes by the hour? The Chang and DeLeon laboratories at the University of Chicago walk through their answer: continuous-culture bioreactors that keep faecal-derived communities alive and evolving for weeks — dosing nutrients such as inulin and palmitic acid, and reading the response at strain-level resolution with the H.E.L BioXplorer.

Featuring Dr Eugene Chang, Dr Orlando (Landon) DeLeon, Dr Candace Cham, Jason Koval and Karen Lolans of the University of Chicago Biological Sciences Division, with a live Q&A. Hosted by Dr Sina Ehsani, Americas Sales Manager, H.E.L Group. Recorded 25 June 2026 · 65 minutes.

Jump to a section

  • 00:00 — Welcome and agenda — Dr Sina Ehsani, H.E.L Group
  • 02:37 — Dr Eugene Chang — the microbiome’s vital role
  • 03:56 — Dr Landon DeLeon — precision medicine and dysbiosis
  • 06:49 — Dr Candace Cham — in vivo models for microbiome research
  • 09:35 — Jason Koval — in vitro and organoid models
  • 12:11 — Karen Lolans — why continuous-culture bioreactors
  • 15:24 — The bioreactor system explained
  • 20:12 — Reactor demo in the lab
  • 21:35 — Advantages and limitations of bioreactors
  • 24:30 — Community assembly and experimental design
  • 28:39 — Inulin study — timeline and results
  • 35:51 — Palmitic acid study
  • 39:22 — Strain-level dynamics
  • 41:30 — Dr Landon DeLeon — rich data and computational modelling
  • 46:59 — Live Q&A with the panel

BioXplorer is a parallel bioreactor platform for microbiome research: independently controlled vessels, anaerobic operation, automated feeding and sampling — stable, reproducible communities over days to weeks. See the BioXplorer 400 →  ·  Ask a specialist →

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