The BioXplorer 400 has four bioreactors, allowing working volumes from 120 ml to 400ml, each meticulously optimized for aerobic fermentation. These bioreactors form the foundation of your bioprocessing endeavors, allowing you to undertake up to four parallel bioprocesses simultaneously. Whether it’s in-depth experimentation, parallel screening, or accelerated research, the BioXplorer 400 offers many possibilities.
Flexibility & Control
The wide range of probes available with the BioXplorer 400 enables the monitoring of critical parameters for the bioprocess for in-depth characterization. The responsiveness of WinISO allows for the fine control of critical parameters in fermentation through the implementation of automated feedback loops.
BioXplorer 400 is an incredible tool for the characterization and optimization of processes. The customizable configuration of the bioreactors allows for the careful selection of the parameters to track during the fermentation. With a choice of agitation, either magnetic or overhead, which enables a wider range of impellor speeds, allowing cultivation of shear sensitive cells at lower speeds. Higher impellor speeds increase gas transfer for increased cell densities or product yields.
The following are a list of some technical publications which highlight the use of the equipment.
Jonathan Tellechea-Luzardo, Leanne Hobbs, Elena Velázquez, Lenka Pelechova, Simon Woods, Víctor de Lorenzo and Natalio Krasnogor
https://www.nature.com/articles/s41467-022-28350-4(Subscription or purchase maybe required for full access)
M.Roger, T.C. Reed, F. Sargent
https://doi.org/10.1101/2021.01.06.425572(Subscription or purchase maybe required for full access)
T. J. Hanly, A.R. Tiernan, M.A. Henson
https://doi.org/10.3182/20131216-3-IN-2044.00002(Subscription or purchase maybe required for full access)