AutoMATE

Linear, automated parallel synthesis platform

AutoMATE is a linear automated parallel synthesis platform designed for chemical synthesis, process development, and design of experiment screening. It features independently controlled reactors with flexible configurations to support a wide range of applications, including catalyst screening and crystallization studies. With advanced automation and an extended temperature range, AutoMATE enables precise, scalable, and efficient experimentation.

AutoMATE
Parallel
Independent reactors
Up to 500 mL
Vessel volumes
−40 to 350 °C
Extended temp range
Overhead
Stirring for viscous
Automated
Multi-step recipes
Online calorimetry
+ FTIR / Raman

Overview

Automated Parallel Synthesis Platform

Auto-MATE is a flexible automated reactor system designed for parallel synthesis and process optimization. Its linear platform supports multiple independently controlled reactors, making it ideal for design of experiment studies and complex chemical processes. Compared to more compact systems, Auto-MATE is suited to demanding applications requiring greater flexibility, higher performance, and easier customization.

Flexible Reactor Configuration

The system supports a wide range of reactor types, including glass and metal vessels with volumes up to 500 mL. It can be integrated with catalyst screening reactor blocks, enabling efficient evaluation of catalytic reactions. Compatibility with high pressure, vacuum, and continuous sampling systems ensures adaptability across different chemistries and processes.

Enhanced Functionality and Integration

Auto-MATE supports a wide range of additional modules, including liquid dosing and sampling, gas feed control, reflux and inerting options, and online calorimetry. Integration with analytical tools such as FTIR, Raman, and particle sizing probes enables deeper process insight and real time monitoring.

Scalable and Customizable Design

The modular design of Auto-MATE allows for easy expansion and customization to meet evolving research needs. This makes it a powerful solution for laboratories seeking a scalable automated platform for chemical synthesis and process development.

Key specifications

ReactorsMultiple, independently controlled (linear platform)
Vessel typesGlass, stainless steel or Hastelloy, up to 500 mL
Temperature controlAmbient to 250 °C standard; options −40 to 350 °C; individual mantles, >100 °C between reactors
StirringOverhead agitation (standard, for viscous systems); optional suspended agitation
Pressure & vacuumHigh-pressure and vacuum systems available
Catalyst screeningIntegrates with catalyst screening reactor blocks
Online calorimetryAvailable
SamplingActive pumps, dip tubes, automated level control or multisampling
Reagent additionAutomated liquid & gas feeds, plus volumetric syringe pumps (high & low pressure)
SensorsTemperature, pressure, pH, turbidity, conductivity; third-party probes (in-situ FTIR, particle sizing, Raman)
Condenser optionsQuick-connect condensing & inerting for larger reactors (condensers removable without cooling-liquid spillage); reflux & inerting block with adapters for vials, tubes and reactors

Applications

Chemical synthesisProcess developmentDesign of Experiment (DOE) screeningCatalyst screeningCrystallization studiesProcess optimization

Software, control & safety

AutoMATE is controlled by advanced software enabling automated workflows with multi-step recipes, real-time data logging and feedback control — consistent, repeatable experiments and more efficient process development.

Configurable reaction-detection and automatic shutdown procedures, with integrated hardware and software safeguards, ensure safe operation even under demanding conditions.

See our application notes for worked AutoMATE examples.

Frequently asked questions

What is AutoMATE used for?
A linear automated parallel synthesis platform for chemical synthesis, process development and Design-of-Experiment (DOE) screening — including catalyst screening and crystallization studies.
How is it different from PolyBLOCK?
AutoMATE is a linear platform suited to more demanding applications needing greater flexibility, higher performance and easier customization, with an extended temperature range.
What temperature range does it cover?
Ambient to 250 °C as standard, with options from −40 to 350 °C; individual heating mantles allow more than 100 °C difference between reactors.
What vessels and volumes?
Glass, stainless steel or Hastelloy up to 500 mL, and it can integrate catalyst screening reactor blocks.
Can it run high-pressure work or calorimetry?
Yes — high-pressure and vacuum systems, plus online calorimetry and probe integration (in-situ FTIR, Raman, particle sizing).
Is it customisable to my process?
Yes — a modular design for easy expansion and customization to evolving research needs. Customisation is central to H.E.L’s approach.

Selected publications

Subscription or purchase may be required for full access. View all publications →

Explore the chemical synthesis range

Related reading

Ready for demanding parallel synthesis?

Talk to a specialist about AutoMATE for DOE, catalyst screening and scale-up.

“We chose H.E.L’s AutoMATE II batch-reactor array — professional advice, reactors built to specification, and thorough on-site training. The associated software is very intuitive and user-friendly, and any issues were resolved quickly by the very helpful team at H.E.L.” — Queen’s University, Belfast

More testimonials →