BioVIS

Inline, non-invasive cell-density monitoring

A probe for inline monitoring of total cell growth and biomass in your bioreactor — track and log culture growth kinetics in real time, without sampling. Compatible with all major bioreactor brands and fully customisable to your requirements.

BioVISBioVIS
Real-time
Cell-density tracking
No sampling
No media loss
0–150 °C
Operating temp
0–10 bar
Pressure
Multiplex
Multi-reactor
All brands
Compatibility

Why choose BioVIS?

Non-invasive

Reduces or eliminates the need for online sampling.

Real-time kinetics

Track and log total cell density continuously.

No media loss

No reduction in culture volume from sampling.

Fits any vessel

Probe lengths customisable; works with all major bioreactor brands.

Specifications

MonitorsTotal cell density & biomass
MeasurementInline, non-invasive (no sampling)
Operating temperature0–150 °C
Pressure0–10 bar
SterilizationSteam-sterilizable to 200 °C · autoclavable
ProbeCustomisable length for any vessel
CompatibilityAll major bioreactor brands
VariantsStandard · Multiplex (multi-reactor)

Integration & compatibility

BioVIS integrates directly into your bioreactor for continuous, in-situ monitoring — no sampling required.

  • Probe lengths customisable for any vessel size; compatible with all major bioreactor brands
  • Optional integrated data-logging, with additional temperature and pH monitoring
  • The BioVIS Multiplex variant tracks total cell density across multiple parallel cultures
  • Steam-sterilizable to 200 °C and autoclavable
  • Supplied and supported across the H.E.L bioreactor range — BioXplorer 100, BioXplorer 400, BioXplorer 400P, BioXplorer 5000

Applications

High-throughput bioprocess developmentCell cultureMicrobial fermentationParallel cultivationGrowth-kinetics studies

Frequently asked questions

What does BioVIS measure?
Total cell growth and biomass, inline and continuously, so culture growth kinetics can be tracked and logged in real time.
Does BioVIS require sampling?
No — it is non-invasive and in-situ, which reduces contamination risk and preserves culture-media volume.
What temperature and pressure can it withstand?
It operates from 0 to 150 °C and up to 10 bar, and is steam-sterilizable to 200 °C as well as autoclavable.
Is BioVIS compatible with my bioreactor?
Yes — probe lengths are customisable for any vessel size and it is compatible with all major bioreactor brands.
Is there a multi-reactor version?
Yes — the BioVIS Multiplex tracks total cell density across multiple parallel cultures for high-throughput workflows.

Related reading

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