BioXplorer 100 | bench-top, parallel 8 bioreactor platform
Vessel Types and Volumes
- Reusable glass bioreactors are appropriate for a wide range of applications at atmospheric pressure.
- All reactors are suitable for autoclaving, with auto-cleavable probes as standard.
- Uniquely developed head plates to house all feeds and probes.
- Working volumes ranging from 20 to 100 mL.
- Bioreactor geometry that mimics production-scale systems.
- -50 ⁰C to 250 ⁰C as standard (circulator dependent).
- Fine temperature control, with fluctuations normally lower than ±0.05 ⁰C
- Stainless steel reactors for standard or elevated pressure (up to 10 bar/145 PSI) fermentations.
- Through active pumps, manual dip tubes, automated level control, or multisampling units, like the ASU.
- Temperature, pressure, pH, DO, turbidity, conductivity.
- Optional: Integration of third-party probes, such as in-situ FTIR, particle sizing probes, and Raman probes.
- 250 up to 1500 rpm via suspended magnetic agitation.
- 0 up to 1500 rpm via overhead stirring.
- Through fully automated liquid and gas feeds as well as volumetric syringe pumps. These solutions can be applied to both high and low-pressure systems.
- All relevant inputs can be logged, enabling automated monitoring and, where appropriate, feedback control of the reactor system
Intelligent Software Control and Analysis
- The labCONSOL control software from H.E.L operates the BioXplorer 100 system, thereby allowing complicated, completely automated experiments to run without the need to be monitored. This allows:
- Multi reactor control with unrestricted step recipe planning, where plans can be altered at any time without process interruption
- User defined data logging with customizable tabular and graphical displays
- Starting and stopping reactors simultaneously or individually
- Export data functions and integration with in-house record keeping systems and electronic lab notebooks
- Include automatic user-configurable reaction monitoring and shutdown procedures, to ensure user safety.
Automatic hardware and software fail-safes are installed on every system.
- The use of a H.E.L BioXplorer in fermentations of Cupriavidus necator H16 at elevated pressure using CO2 as the sole carbon source
- Characterization of the maximum heating performance for the multi-reactor PolyBLOCK 8
- Characterization of the cooling performance for the multi-reactor PolyBLOCK 8
- Characterization of the heating performance for the multi-reactor PolyBLOCK 8
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