PolyBLOCK | Compact Automated Parallel Synthesis Platform

My experience with H.E.L dates since 2005. During these years H.E.L was the provider of the most important lab equipment with the help of which I developed many different API pharmaceutical processes in the companies l worked for including Merck, Pfizer, and Theravance. The versatility of the automated lab reactors (AutoLAB), the ease of use of and the accuracy of the TSu and Simular systems, as well as the flexibility of the PolyBLOCK made my work much easier and accurate. I would like to mention the great relationship I established with the service engineers and the sales people at H.E.L. With their help I was able to customize the software and the hardware of the equipment to our specific needs. This readiness to accommodate each customer’s specific needs gives H.E.L the edge over their competitors and makes them the preferred vendor for pharmaceutical lab equipment.

Theravance Inc – USA

With the polyblock 4 system significant time savings have been achieved compared to using conventional laboratory reactors while at the same time obtaining more information on the process studied. The system has given reproducible process control making it very useful in DOE experiments on a precise recrystallisation where variations due to operational error had to be minimised. Also with the flexibility in reactor size the process was run on smaller scale than previously reducing the demand for a valuable process intermediate.

Almac Group – United Kingdom

A versatile time saving tool for QBD & DOE study for all kind of chemistry, crystallization, & even integrated with Calorimetric study. H.E.L motto “Better Chemistry – Faster” matches with output of instrument giving better control over chemistry & faster result. Thanks for making our work simple.

Cipla – India

We purchased a PolyBLOCK 4 zone system in November of 2012 and the system was delivered on time and to our specification. The PolyBLOCK has increased throughput by allowing us to easily and efficiently run multiple reactions. Our system has proven to be very reliable and we utilize it on a daily basis. We are very satisfied with our purchase of the PolyBLOCK 4 and the advice and technical support offered by HEL.

Secant Medical – USA

PolyBlock PB4 is ideal and best suited for Pharmaceutical application in terms of flexibility, upgradability for various applications like pH monitoring and control, solubility and MSZW for crystallisation , high pressure Hydrogenation , Online Real Time calorimetry, reflux & inerting , PAT tools in future , overhead motor stirring , extended temperature range -80 to 250 ( depends on the chiller being used with the PB4 ).

Dr D.Y. Patil - Institute of Pharmaceutical Sciences – India

The PolyBLOCK 4 is simple to use for all chemists and biochemists in our company. It allows us to carry out more reactions at a time, under very good temperature control. We also operate the PolyBlock overnight under pre-programmed procedures, to save a lot of precious time. We use different sizes of glassware in the same block, which allows us to investigate our chemistry at small scale, and then scale-up using the same equipment and pre-programmed procedure.

BioCompatibles UK Ltd – United Kingdom

My role within the Green Chemistry Centre at the University of York (UK) is as Clean Synthesis Technology Platform Leader. Through this role I am currently supervising work being undertaken studying the application of heterogeneous catalysts and high-pressure gases for the conversion of biomass derivable compounds. As such our group has recently purchased three high-pressure reactors from H.E.L Ltd. To assist in the evaluation of our heterogeneous catalysts it is vital that stirring in the reactor vessel is control effectively and the reactor designs from H.E.L Ltd. achieve this by use of a suspended stirrer-bar system. As a result of our gas addition requirements some modification to the standard reactor designs were necessary, this being an area that H.E.L Ltd. were especially helpful in catering to our needs. From first contact with H.E.L (via Andrew Coleman), through reactor design and finally to reactor delivery H.E.L Ltd have been a pleasure to work. Throughout our interaction H.E.L Ltd. has proven to be knowledgeable, inventive and very efficient in supporting our research needs. I wholeheartedly support H.E.L Ltd. as a reliable, affordable, professional and helpful company for the design and manufacture of high-pressure equipment, and I certainly intend to use them again when such services are required.

University of York – York, England

H.E.L’s PolyBLOCK is a classic invention that allows process development at the fastest rate. We have developed a process for 9 steps carbohydrate project in just 45 days with the help of PolyBLOCK.

Dr Nikhil Jadhav - Aarti Industries