BioXplorer 100

Parallel bioreactor screening in as little as 50 mL

Accelerate bioprocess development with 8 independent bioreactors, real-time monitoring and fully automated control — built for accuracy, flexibility and reproducible results, and fully customisable to your requirements.

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Parallel reactors

50–150 mL

Working volume

Automated

Control

Real-time

Monitoring

0–130 °C

Temperature

up to 1500 rpm

Agitation

Why choose the BioXplorer 100?

Faster development

Run experiments in parallel and accelerate optimisation.

Lower costs

Modest working volumes cut media and reagent use.

Better control

Independent pH, DO, temperature and feeding in every reactor.

Actionable insights

Real-time data and WinISO tools for faster, data-driven decisions.

Specifications

Number of independent parallel bioreactors	8
Bioreactor material	Glass body, stainless steel lid
Total volume	50-150ml
Sterilization	Autoclavable bioreactors (including sensors)
Temperature Range	0 – 130 °C
Temperature resolution	0.1 °C
Stirrer drive	Magnetically driven captive impeller
Stirrer speed	250 – 1500 rpm
Auto re-couple	Yes
Liquid additions with independent control for each bioreactor	2 as standard, options for up to 2 additional liquid feeds
Gas additions	1 set of 8 mass flow controllers allowing independent control for each reactor as standard, option for 1 additional set
Standard options for MFC calibration	Air, oxygen as option
Gas spargers	1
Exhaust gas	Peltier cooled condenser
pH control	1-way control (2-way control optional)
pH Sensing	0-14
Polarographic DO sensing	Standard
DO control	Gas/liquid flow rate, stirrer speed
BioVIS cell-density monitoring	Optional
Tandem off-gas analysis	Optional
Foam/Level detection	Optional
Control PC and software	WinISO control software (pre-installed)

Software

The H.E.L WinISO software runs every reactor with fully independent, automated control — advanced strategies from sensor feedback, time-based profiles or event detection, with real-time logging and .csv export.

Fully customisable, it controls the complete range of process parameters — temperature, stirrer speed, dissolved oxygen, pH, gas flow rates, liquid feed rates and foam & level detection.

Applications

CO₂ fermentationSustainable aviation fuelIndustrial biotechnologyFood biotechnologySynthetic biologyWaste-gas fermentation

Frequently asked questions

What is the BioXplorer 100 used for?

A bench-top, eight-reactor platform for optimising aerobic fermentations and high-throughput bioprocess screening — from E. coli cultivation and gas fermentation through to biofuel and SAF development.

Is the system customisable to my process?

Yes. Every BioXplorer 100 is configured to your requirements — probes, sensors, gas and liquid feeds are all specified around your application. Customisation to the customer’s process is central to H.E.L’s approach.

How many reactors and what working volume?

Eight parallel, independently-controlled bioreactors with working volumes of 50–150 ml (glass body, stainless-steel lid, fully autoclavable including sensors).

What temperature and agitation does it offer?

0 to 130 °C with 0.1 °C resolution, and magnetically-driven captive-impeller stirring from 250 to 1500 rpm.

What does the control software do?

The H.E.L WinISO software gives fully independent control of all eight reactors — automated stirring, gas and liquid additions from sensor feedback, with real-time logging and .csv export.

What monitoring options are available?

pH (0–14) and polarographic dissolved-oxygen sensing as standard; optional BioVIS for online cell-density monitoring and foam/level detection; optional Tandem off-gas analysis for OUR, CPR and RQ.