Materials and Method
For these characterizations, the PolyBLOCK 4 was used in standard laboratory conditions. Large SS316 and glass reactors were used; the SS316 reactors of 300 mL and 500 mL were placed in positions 1 and 3 (Figure 1). The 500 mL and 300 mL glass reactors were placed in positions 2 and 4 of the reactor (Table 1).
Methanol (CAS no.: 67-56-1), and Silicone oil (Huber P20-275-50) were the solvents used for these tests. In all cases, the stirring was provided via magnetically coupled agitation provided by the PolyBLOCK in-built magnetic stirrer at 400 rpm. Six-blade PTFE Rushton impellers were used in both the glass and metal reactors. In addition, a Huber Unistat 430 was attached to the PolyBLOCK to provide active cooling. The Unistat 430 is larger than the recommended circulator for a PolyBLOCK. However, it has similar cooling and heating capacities to other smaller models, and thus allows for a performance comparison.
labCONSOL® was used to operate the PolyBLOCK 4. The software can control the reactor in several modes, such as Constant Reactor Temperature or Heat/Cool Reactor (ramping reactor temperature). Heat/Cool Reactor changes the reactor temperature at a defined rate -see Figure 2.
In contrast, Constant Reactor Temperature Control (Figure 3) heats the reactor contents to a specified temperature as quickly as possible. Both heating modes were investigated.