H.E.L has a broad range of products that are used for many different applications. Our equipment has been used in many cutting-edge studies and scientific breakthroughs. Here is a selection of publications that feature our products and have been organized into application area.
Click the links to the left to direct you to the publications relating to your chosen application area:
Achieving pH and Qr oscillations in a palladium-catalysed phenylacetylene oxidative carbonylation reaction using an automated reactor system
Author(s): K.Novakovic, C.Grosjean, S.K.Scott, A.Whiting, M.J.Willis, A.R.Wright
Date: 01/02/2007
H.E.L Product(s) used
Control of Supersaturation in a Semibatch Antisolvent Crystallization Process Using a Fuzzy Logic Controller
Author(s): H. Hojjati, M. Sheikhzadeh, and S. Rohani
Date: 11/01/2007
H.E.L Product(s) used
Safe and Productive Operation of Homogeneous Semibatch Reactors. II. The Nitration of N-(2-Phenoxyphenyl) Methane Sulfonamide
Author(s): Francesco Maestri, Leonardo Re Dionigi, Renato Rota, Lucia Gigante, Angelo Lunghi, and Paolo Cardillo
Date: 31/10/2006
H.E.L Product(s) used
Development of a Scalable and Safe Procedure for the Production of (3R)-3-(2,3-Dihydro-1-benzofuran-5-yl)-1,2,3,4-tetrahydro-9H-pyrrolo[3,4-b]- quinolin-9-one, an Intermediate in the Synthesis of PDE-V Inhibitors RWJ387273 (R301249) & RWJ444772 (R290629)
Author(s): Bert Willemsens, Ivan Vervest, Dominic Ormerod, Wim Aelterman, Christine Fannes, Narda Mertens, István E. Markó, and Sebastien Lemaire
Date: 12/07/2006
H.E.L Product(s) used
Venting of a runaway organic peroxide decomposition in viscous solvents on pilot scale
Author(s): T.J. Snee, L. Cuscó, J.A. Hare, D.C. Kerr & M. Royle
Date: 20/06/2006
H.E.L Product(s) used
Miniature bioreactors: current practices and future opportunities
Author(s): F. Baganz and J.L.Betts
Date: 01/05/2006
H.E.L Product(s) used
Nitrilase-Catalysed Desymmetrisation of 3-Hydroxyglutaronitrile: Preparation of a Statin Side-Chain Intermediate
Author(s): Sophie Bergeron, David A. Chaplin, John H. Edwards, Brian S. W. Ellis, Catherine L. Hill, Karen Holt-Tiffin, Jonathan R. Knight, Thomas Mahoney, Andrew P. Osborne, and Graham Ruecroft
Date: 01/04/2006
H.E.L Product(s) used
Critical Assessment of Pharmaceutical Processes A Rationale for Changing the Synthetic Route
Author(s): Mike Butters, David Catterick, Andrew Craig, Alan Curzons, David Dale, Adam Gillmore, Stuart P. Green, Ivan Marziano, Jon-Paul Sherlock, and Wesley White
Date: 08/03/2006
H.E.L Product(s) used
Towards an Information-Rich Process Development. Part I: Interfacing Experimentation with Qualitative/Semiquantitative Modelling
Author(s): Divine A. Obenndip and Paul N. Sharratt
Date: 08/03/2006
H.E.L Product(s) used
Polymorph and Particle Size Control of PPAR Compounds PF00287586 and AG035029
Author(s): Billie J. Kline,* James Saenz, Nebojsˇa Stankovic ́, and Mark B. Mitchell
Date: 01/03/2006
H.E.L Product(s) used
Thermal Hazards of the Vilsmeier−Haack Reaction on N,N-Dimethylaniline
Author(s): Marcus Bollyn
Date: 03/11/2005
H.E.L Product(s) used
Design and Characterisation of Parallel Miniature Bioreactors for Bioprocess Optimisation and Scale-up
Author(s): N.K. Gill
Date: 01/11/2005
H.E.L Product(s) used
Polymerization Hazard
Author(s): David J. am Ende, David R. Bill, David B. Ripin, and Nancy A. Sage
Date: 14/10/2005
H.E.L Product(s) used
Modeling the Precipitation of l-Glutamic Acid via Acidification of Monosodium Glutamate
Author(s): A. Borissova, Y. Jammoal, K. H. Javed, X. Lai, T. Mahmud, R. Penchev, K. J. Roberts, and W. Wood
Date: 16/04/2005
H.E.L Product(s) used
Isothermal reaction calorimetry as a tool for kinetic analysis
Author(s): Andreas Zogg, Francis Stoessel, Ulrich Fischer, Konrad Hungerbühler
Date: 01/09/2004
H.E.L Product(s) used
Use of reaction calorimetry in thermal risk assessment studies and safe design of batch reactions that can lead to a runaway: application on hydrogen peroxide
Author(s): M. Papadaki
Date: 01/06/2004
H.E.L Product(s) used
Thermal hazards evaluation for sym-TCB nitration reaction using thermal screening unit (TSU)
Author(s): A. Nandi, V. Sutar & S. Bhattacharyya
Date: 01/06/2004
H.E.L Product(s) used
Monitoring and Feedback Control of Supersaturation Using ATR-FTIR to Produce an Active Pharmaceutical Ingredient of a Desired Crystal Size
Author(s): Vincenzo Liotta* and Vijay Sabesan
Date: 01/05/2004
H.E.L Product(s) used
On-Line Monitoring of a Crystallization Process
Author(s): Patricia Mougin, Alistair Thomas, Derek Wilkinson, Graeme White, Kevin J. Roberts, Norbert Herrmann, Robert Jack and Richard Tweedie
Date: 16/04/2004
H.E.L Product(s) used
Different scale experimental techniques to approach the problem of substances generated in the loss of control of chemical systems: a study on ethyl diazoacetate decomposition
Author(s): Katia Marsanich, Federica Barontini, Valerio Cozzani, Alain Creemers, Ronald Kerstend
Date: 01/01/2004
H.E.L Product(s) used
