Process Safety and Scale-Up

H.E.L has a broad range of products that are used for many different applications. Our equipment has been used in many cutting-edge studies and scientific breakthroughs. Here is a selection of publications that feature our products and have been organized into application area.

Click the links to the left to direct you to the publications relating to your chosen application area:

1 - 20 of 41 Publications
Thermal Hazards of Synthesizing a Grignard Reagent under Different Dosing Rates

Author(s): Wei Wang , Jiancun Gao , Chenguang Shi, Shengnan Wang, Yujing Li, Xiong Dai, and Tianmeng Jiang

Date: 01/03/2022

Product(s) used

A detailed kinetic model for the thermal decomposition of hydroxylamine

Author(s): Gianmaria Pio, Paolo Mocellin, Chiara Vianello, Ernesto Salzano

Date: 01/08/2021

Product(s) used

Analysis of thermal hazards of tertbutylperoxy2ethylhexyl carbonate by calorimetric technique

Author(s): Juan Zhou, Chen-Ye Wei, Min Hua, Xu-Hai Pan, Xin-Miao Liang, An-Dong Yu, Cyril G. Suetor & Jun-Cheng Jiang

Date: 06/03/2021

Product(s) used

Continuous Safety Improvements to Avoid Runaway Reactions: The Case of a Chloro-Thiadiazole Intermediate Synthesis toward Timolol

Author(s): Alessandro Agosti, Silvia Panzeri, Federico Gassa, Massimo Magnani, Giulia Forni, Marco Quaroni, Lazzaro Feliciani and Giorgio Bertolini

Date: 19/05/2020

Product(s) used

Study on thermal stability of nickel-rich/silicon-graphite large capacity lithium ion battery

Author(s): Hang Li, Xiangbang Kong, Chaoyue Liu, Jinbao Zhao

Date: 01/10/2019

Product(s) used

Explosion Hazards of Sodium Hydride in Dimethyl Sulfoxide, N,N-Dimethylformamide, and N,N-Dimethylacetamide

Author(s): Qiang Yang, Min Sheng, James J. Henkelis, Siyu Tu, Eric Wiensch, Honglu Zhang, Yiqun Zhang, Craig Tucker, and David E. Ejeh

Date: 10/08/2019

Product(s) used

An Alternative Scalable Process for the Synthesis of 4,6-Dichloropyrimidine-5-carbonitrile

Author(s): Bin Zhang, Huixin Yan, Chongfeng Ge, Bo Liu and Zhenping Wu

Date: 01/11/2018

Product(s) used

Thermal behaviour of Peracetic Acid for the epoxydation of vegetable oils in the presence of catalyst

Author(s): Chiara Vianello, Ernesto Salzano, Giuseppe Maschio

Date: 01/05/2018

Product(s) used

Zero-Order Versus Intrinsic Kinetics for the Determination of the Time to Maximum Rate under Adiabatic Conditions (TMRad): Application to the Decomposition of Hydrogen Peroxide

Author(s): Lamiae Vernières-Hassimi, Amine Dakkoune, Lokmane Abdelouahed, Lionel Estel, and Sébastien Leveneur

Date: 24/06/2017

Product(s) used

Autonomous reorganization of the oscillatory phase in the PdI2 catalyzed phenylacetylene carbonylation reaction

Author(s): Julie Parker & Katarina Novakovic

Date: 11/02/2016

Product(s) used

Experimental sensitivity analysis of the runaway severity of Dicumyl peroxide decomposition using adiabatic calorimetry

Author(s): Olga J. Reyes Valdesa, Valeria Casson Moreno, Simon P. Waldram, Luc N. Véchot, M. Sam Mannan

Date: 10/10/2015

Product(s) used

Safety Parameters and Preliminary Decomposition Kinetic of Organo-Peroxy Acids in Aqueous Phase

Author(s): Chiara Vianello, Ernesto Salzano , Giuseppe Maschio*

Date: 01/05/2015

Product(s) used

Thermal Decomposition Analysis and Safety Study on Di-tert-butyl Peroxide

Author(s): Lv Jiayu, Chen Wanghua, Chen Liping, Tian Yingtao, Sun Xin

Date: 01/10/2012

Product(s) used

Calorimetric studies on the thermal stability of methyl ethyl ketone peroxide (MEKP) formulations

Author(s): Stephen R.Graham, Robert Hodgson, Luc Vechota, M.Iqbal Essa

Date: 01/11/2011

Product(s) used

2-Bromo-3-(cyclohexyloxy)acrylaldehyde: An Isolable Enol Ether of Bromomalonaldehyde Suitable for Use in the Manufacture of Imidazolecarboxaldehydes

Author(s): Terrence J. Connolly*, Michael W. Disharoon, Vladimir Dragan, Joseph J. Lewis, Peter Wehrenberg, and Ralph Zhao

Date: 21/10/2010

Product(s) used

Aminodifluorosulfinium Salts: Selective Fluorination Reagents with Enhanced Thermal Stability and Ease of Handling

Author(s): Alexandre L’Heureux, Francis Beaulieu, Christopher Bennett, David R. Bill, Simon Clayton, François LaFlamme, Mahmoud Mirmehrabi, Sam Tadayon, David Tovell, and Michel Couturier

Date: 21/04/2010

Product(s) used

The influence of reaction temperature on the oscillatory behaviour in the palladium-catalysed phenylacetylene oxidative carbonylation reaction

Author(s): Katarina Novakovic,* Ankur Mukherjee, Mark Willis, Allen Wright and Steve Scott

Date: 01/08/2009

Product(s) used

A Convenient and Stable Synthon for Ethyl Azide and Its Evaluation in a [3 + 2]-Cycloaddition Reaction under Continuous-Flow Conditions

Author(s): Rob Tinder, Roger Farr, Richard Heid, Ralph Zhao, Randy S. Rarig, Jr., and Thomas Storz

Date: 28/05/2009

Product(s) used

Simple Procedure for Optimally Scaling-up Fine Chemical Processes. I. Practical Tools

Author(s): Francesco Maestri, Sabrina Copelli, Renato Rota*, Lucia Gigante, Angelo Lunghi, and Paolo Cardillo

Date: 12/01/2009

Product(s) used

Kinetics Estimation and Single and Multi-Objective Optimization of a Seeded, Anti-Solvent, Isothermal Batch Crystallizer

Author(s): M. Trifkovic, M. Sheikhzadeh, and S. Rohani

Date: 01/02/2008

Product(s) used

1 - 20 of 41 Publications

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