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Process Safety and Scale-Up
H.E.L has a broad range of products that are used for many different applications. Our equipment has been used in many cutting-edge studies and scientific breakthroughs. Here is a selection of publications that feature our products and have been organized into application area.
Click the links to the left to direct you to the publications relating to your chosen application area:
61 - 80 of 107 Publications
Reaction calorimetric analysis of batch cooling crystallization processes: studies of urea in supersaturated water–methanol solutions
Author(s): Xiaojun Lai, Kevin J. Roberts, Joakim Svensson and Graeme White
Date: 03/02/2011
Product(s) used
2-Bromo-3-(cyclohexyloxy)acrylaldehyde: An Isolable Enol Ether of Bromomalonaldehyde Suitable for Use in the Manufacture of Imidazolecarboxaldehydes
Author(s): Terrence J. Connolly*, Michael W. Disharoon, Vladimir Dragan, Joseph J. Lewis, Peter Wehrenberg, and Ralph Zhao
Date: 21/10/2010
Product(s) used
Aminodifluorosulfinium Salts: Selective Fluorination Reagents with Enhanced Thermal Stability and Ease of Handling
Author(s): Alexandre L’Heureux, Francis Beaulieu, Christopher Bennett, David R. Bill, Simon Clayton, François LaFlamme, Mahmoud Mirmehrabi, Sam Tadayon, David Tovell, and Michel Couturier
Date: 21/04/2010
Product(s) used
The influence of reaction temperature on the oscillatory behaviour in the palladium-catalysed phenylacetylene oxidative carbonylation reaction
Author(s): Katarina Novakovic,* Ankur Mukherjee, Mark Willis, Allen Wright and Steve Scott
Date: 01/08/2009
Product(s) used
A New Autocatalytic Thioacetate-Enal Addition Reaction: A Michael Addition or Not?
Author(s): Lijun Liu, Maria Papadaki, Elen Pontiki, Panagiota Stathi, William J.Rogers and M. Sam Mannan
Date: 15/06/2009
Product(s) used
Isothermal decomposition of hydroxylamine and hydroxylamine nitrate in aqueous solutions in the temperature range 80–160 ◦C
Author(s): LijunLiua, Maria Papadaki, Eleni Pontiki, Panagiota Stathi, William J. Rogers and M. Sam Mannan
Date: 15/06/2009
Product(s) used
A Convenient and Stable Synthon for Ethyl Azide and Its Evaluation in a [3 + 2]-Cycloaddition Reaction under Continuous-Flow Conditions
Author(s): Rob Tinder, Roger Farr, Richard Heid, Ralph Zhao, Randy S. Rarig, Jr., and Thomas Storz
Date: 28/05/2009
Product(s) used
Thermal Behavior of Aqueous Solutions of Hydroxylamine During Isothermal and Isoperibolic Decomposition in a Closed System
Author(s): Maria I. Papadaki, Eleni Pontiki, Lijun Liu, William J. Rogers, and M. Sam Mannan
Date: 19/05/2009
Product(s) used
Simple Procedure for Optimally Scaling-up Fine Chemical Processes. I. Practical Tools
Author(s): Francesco Maestri, Sabrina Copelli, Renato Rota*, Lucia Gigante, Angelo Lunghi, and Paolo Cardillo
Date: 12/01/2009
Product(s) used
A Practical Method For Stabilizing Lithiated Halogenated Aromatic Compounds
Author(s): Thimma Rawalpally, Yaohui Ji, Ashish Shankar, William Edwards, Joshua Allen, Yong Jiang, Thomas P. Cleary, and Michael E. Pierce
Date: 15/10/2008
Product(s) used
Advanced kinetics-based simulation of time to maximum rate under adiabatic conditions
Author(s): B. Roduit, W. Dermaut, A. Lunghi, P. Folly, B. Berger & A. Sarbach
Date: 01/07/2008
Product(s) used
Kinetics Estimation and Single and Multi-Objective Optimization of a Seeded, Anti-Solvent, Isothermal Batch Crystallizer
Author(s): M. Trifkovic, M. Sheikhzadeh, and S. Rohani
Date: 01/02/2008
Product(s) used
Fuzzy logic and rigid control of a seeded semi-batch, anti-solvent, isothermal crystallizer
Author(s): M. Sheikhzadeh M. Trifkovic and S. Rohani
Date: 01/02/2008
Product(s) used
Utilising high throughput technologies for the determination of the reaction network of the L-proline catalysed aldol reaction
Author(s): Katarina Novakovic, Mark J. Willis and Allen R. Wright
Date: 23/01/2008
Product(s) used
Safety Concerns Regarding the Transportation of Organic Powders on Dry Ice: How CO 2 Adsorption Can Lead to Powder Spills
Author(s): Wim Dermaut*, Jan van Dun, Jan De Kock, Ivan Vervest, and Christine Fannes
Date: 01/01/2008
Product(s) used
The influence of oscillations on product selectivity during the palladiumcatalysed phenylacetylene oxidative carbonylation reaction
Author(s): Katarina Novakovic, Christophe Grosjean, Stephen K. Scott, Andrew Whiting, Mark J. Willis and Allen R. Wrighta
Date: 27/11/2007
Product(s) used
Safety Aspects of a Cyanamide Reaction: Inherent Safe Design through Kinetic Modelling and Adiabatic Testing
Author(s): Wim Dermaut*, Christine Fannes, and Johan Van Thienen
Date: 22/09/2007
Product(s) used
Achieving pH and Qr oscillations in a palladium-catalysed phenylacetylene oxidative carbonylation reaction using an automated reactor system
Author(s): K.Novakovic, C.Grosjean, S.K.Scott, A.Whiting, M.J.Willis, A.R.Wright
Date: 01/02/2007
Product(s) used
Control of Supersaturation in a Semibatch Antisolvent Crystallization Process Using a Fuzzy Logic Controller
Author(s): H. Hojjati, M. Sheikhzadeh, and S. Rohani
Date: 11/01/2007
Product(s) used
Safe and Productive Operation of Homogeneous Semibatch Reactors. II. The Nitration of N-(2-Phenoxyphenyl) Methane Sulfonamide
Author(s): Francesco Maestri, Leonardo Re Dionigi, Renato Rota, Lucia Gigante, Angelo Lunghi, and Paolo Cardillo
Date: 31/10/2006
Product(s) used
