In this section, you will find a library of specific case studies/application notes demonstrating the extensive functionality of how scientists are using H.E.L equipment in all the fields of work, including research, scale-up, and production. These case studies show real results and demonstrate our equipment’s performance in applications for biotechnology, thermal hazards, catalysis, calorimetry, flow chemistry, parallel processing, crystallization, and particle studies. These application notes and case studies are subject to copyright. To use any part of this work, please contact us.

Operating the BioXplorer 100 as a Turbidostat to Maximize High-Density E. coli Cultivation

Operating the BioXplorer 100 as a Turbidostat to Maximize High-Density E. coli Cultivation

The BioXplorer 100 can function as a turbidostat to maintain stable, high-density E. coli cultures. Using its BioVIS probe and WinISO-controlled pumps, it adjusts medium flow based on real-time turbidity. A non-linear calibration curve enables accurate cell density measurements at high biomass, supporting reproducible bioprocess development, consistent physiology studies, and controlled experimental evolution.

The use of a H.E.L BioXplorer in fermentations of Cupriavidus necator H16 at elevated pressure using CO2 as the sole carbon source

The use of a H.E.L BioXplorer in fermentations of Cupriavidus necator H16 at elevated pressure using CO2 as the sole carbon source

In this case study, the H.E.L BioXplorer was used to evaluate microbial fermentation in either autotrophic mode or heterotrophic mode.